This issue has been rated Baa1 (st) / A- (st) / AL (st). The demand was highly diversified geographically, placing 73% outside of Spain, and the high quality of the orders meant that 53% was represented by SRI accounts. In October, the Autonomous Community of Madrid issued its third green bond on the capital market and its second public issue in 2022, with a term of 7 years and a volume of 500 million euros, being mandated to participate in the BBVA issue in its role as green structuring bank, CaixaBank, Credit Agricole CIB, ING and Santander. This transaction is the first issue of the Spanish public sector and one of the first in Europe fully aligned with the green taxonomy of the European Union. This issue has been classified with a rating of A-/Baa1/A-/BBB by S&P, Moody's, DBRS and Fitch respectively. The transaction has received great support from the international investment community, representing 77% of the orders received, with France being the most representative international jurisdiction with 17%, followed by the United Kingdom and Ireland with 16%, Italy with 14%, Germany /Austria with 14%, BeNelux with 9% and other EU countries with 7%. The quality of the book can also be seen in the allocation of the bonds by type of investor, with fund managers being the investors with the highest allocation with 49%, followed by banks with 46%, insurance companies and pension funds with 20%. % and finally “Hedge Funds” representing only 1% of the allocated volume.
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Given the imprecision in risk estimates, eliciting patients’ values and preferences regarding the potential benefits and harms of statins and other lipid-lowering agents remains essential to treatment decisions. The general guidelines for adults in the United States are: Less than 100 milligrams per deciliter (mg/dL): Optimal 100-129 mg/dL: Near or above optimal 130-159 mg/dL: Borderline high 160-189. As a guide, health authorities recommend cholesterol levels should be no higher than 5.5 mmol per litre if there are no other risk factors present, or LDL levels less than 2 mmol/l for those who smoke, have high blood pressure or pre-existing heart disease. In healthy adults, the following ranges are regarded as 'good' levels: Total cholesterol: Levels below 200 mg/dL (5. Finally, the ACC/AHA did not update the Pooled Cohort Equations risk assessment tool, despite widespread recognition that it can significantly overestimate 10-year risk of myocardial infarction and stroke. The treatment goal for individuals with heart disease or blood vessel disease is to reach an LDL of less than 1.8 mmol/L (70 mg/dL). It encourages the expanded use of CAC scoring to guide the decision to start statin therapy, even though no studies have shown that risk stratification based on CAC score reduces cardiovascular morbidity or mortality more than traditional risk factors alone. Also, it may be beneficial to treat patients 20 to 75 years of age who have an LDL-C level of 190 mg per dL or greater with ezetimibe if they have not been able to achieve a 50 reduction in LDL-C. You may not need more cholesterol tests if your cholesterol is in this normal range. For example, the guideline recommends periodic lipid monitoring in patients receiving therapy, even though randomized trials generally prescribed fixed statin doses rather than titrating to LDL-C percentage reductions or threshold levels. A total cholesterol of 180 to 200 mg/dL (10 to 11.1 mmol/l) or less is considered best. LDL-cholesterol less than 2.0 mmol/L HDL-cholesterol greater than 1.0 mmol/L Triglycerides less than 1.7 mmol/L Total cholesterol less than 4.0 mmol/. Editor’s Note: Similar to the 2013 ACC/AHA cholesterol guideline, this guideline has some utility for family physicians but is limited by several recommendations that will be challenging to implement and lack patient-oriented evidence. Since then, tens of thousands more math worksheets have been added. was launched in 2005 with around 400 math worksheets. There are two interactive math features: the math flash cards and dots math game. Our math worksheets are available on a broad range of topics including number sense, arithmetic, pre-algebra, geometry, measurement, money concepts and much more. 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Check for doneness after 8-10 minutes - it may take a few minutes longer.Carefully slide the pizza onto the hot stone (if it isn't sliding, you will need to sprinkle more flour or cornmeal between the pizza and the pizza peel, until it moves.Bake at 410☏ for 15 minutes and sprinkle the remaining parmesan cheese onto the bread. Sprinkle with 1/2 of the parmesan cheese. Place the finished dough onto the prepared pizza peel and add the toppings of your choice. Press fresh garlic cloves into melted butter and give it a good stir.Using your hands or a rolling pin, roll out and stretch the dough until it is approximately 1/8" thick and 12" wide. Sprinkle your work area with a little flour.You can taste it in every bite of our naan, pizza crusts and flatbreads. Using a little flour (enough so it won't stick to your fingers), stretch and shape the dough into a ball. 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Hades Review – The Long, Hard Road Out of Hellġ7 September 2020 Physical description If Zagreus accepts Thanatos' offer, he needs to understand that Thanatos' distant and unsettling silence does not indicate indifference and Zagreus will have to deal with it. He takes things extremely seriously, so when Zagreus says he wants to go further, Thanatos asks him to clarify and hopes that Zagreus doesn't think he's joking. Everyone in the underworld seems to already know how he feels about Zagreus. Proud and hesitant, Thanatos is a "tsundere" who is not honest about his feelings, but also not good at hiding them. As Hypnos becomes more active in his tasks in the House, Thanatos secretly praises him. When Hypnos is at risk of losing his job, Thanatos intervenes. Thanatos tends to ignore or reprimand Hypnos, but he sees it as an incentive to improve. Hypnos tends to be sloppy in his work, while Thanatos is methodical, solemn and completes his tasks in an orderly manner. Thanatos is has a strict code of conduct at work, especially when it comes to his twin brother Hypnos. Zagreus considers listening to this as "a Death Sentence." However, he is surprisingly talkative in combat, announcing his next moves. Thanatos is also reserved, does not open up easily, and does not share details about his private life unless they are related to work. However, Zagreus claims that beneath his prickly exterior, Thanatos is very cordial, respectful, and friendly, deconstructing down the "Ice king". Even when he apologizes, his words can be harsh. To others in the underworld, Thanatos is see a work-loving "sadic perfectionist", insensitive, rude, and always seems to be in a bad mood. He sees death as a compassionate friend responsible for taking mortals to the end of their lives and treats it only as an aspect of his work. Despite his strong work ethic, this does not stop him from moving in the shadows as Thanatos breaks his loyalty vow to the House of Hades by offering his support to Zagreus to help him escape.ĭespite, as the personification of death, Thanatos represents peaceful and non-violent death, removing life in a painless and expected way. The embodied death, Thanatos prioritizes a job well done and likes to keep a perfect record. If he is given nectar during the run right before appearing in the House, he won't be able to be gifted. After a run in which he was encountered, he has a high (but not 100%) chance of appearing in the House. Within the House of Hades, Thanatos can be found in the same hallway where Achilles keeps guard. If Zagreus either kills more enemies than Thanatos does or ties his total, he will award Zagreus a Centaur Heart in addition to the regular room-clear reward. He is immune to damage during the contest, and will not retaliate if struck (he'll just complain). Thanatos occasionally appears at the beginning of regular encounters and challenges Zagreus to see which of them can slay more shades. He apparently dislikes the mortal realm, in particular how bright it can get. His most recent such venture took longer than usual - speculated by Hypnos and Zagreus to be related to the ongoing war - but returns some time after the game's opening. He is one of Nyx's many children and the older twin brother of Hypnos.Īs the embodiment of death, Thanatos has many duties requiring him to venture up into the mortal realm. Chris Saphire Thanatos is the personification of death. |
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